Malaria was not referenced in the "medical books" of the Mayans or Aztecs . European settlers and the West Africans they enslaved likely brought malaria to the Americas in the 16th century.  
We are generating evidence that malaria can be eliminated in diverse geopolitical and transmission zones, including Southern Africa and the Greater Mekong Sub-region. We believe that current tools used more effectively or in novel ways, along with strong partnerships and government commitment, can bring malaria campaigns closer to the “last mile” of elimination. This includes improving the delivery of existing vector-control tools, diagnostics, and drugs; investigating the potential of existing drugs to achieve complete cure at the individual and population levels, including the asymptomatic reservoir; and refining strategies for reaching special populations, such as pregnant women and children under age 5.
Some P. vivax sporozoites do not immediately develop into exoerythrocytic-phase merozoites, but instead, produce hypnozoites that remain dormant for periods ranging from several months (7–10 months is typical) to several years. After a period of dormancy, they reactivate and produce merozoites. Hypnozoites are responsible for long incubation and late relapses in P. vivax infections,  although their existence in P. ovale is uncertain. 
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MMV and Novartis launch patient trial in Africa of first compound from a novel class of antimalarials